I think so, though I'm led to believe that's only an issue with resin or other less mainstream manufacturers.
Resin casters need to use a generous amount of release agent, especially if the casting has deep undercuts. Excessive release agent is not usually a big issue with mainstream maunfacturers, although you might come across it from time to time and it's pretty obvious when it happens. I mostly use hot primers and lacquer based acrylics and other than giving the surfaces a wipe I don't usually wash them with any detergent. So far paint adhesion has not been a problem.